Dr. Now's eldest child, Jonathan, is CEO and co-owner of a production company called Megalomedia (via The Austin Chronicle). Incorporated in 2003, the media company was a creative venture intended to produce documentaries that would not only educate viewers, but motivate them as well. With a degree in business and Christian ministry, the younger Nowzaradan explained in a 2007, "It's fine to make some money, but media can be used for so much more, to communicate a lot of good things, to encourage, to inspire."

In 2010, Megalomedia distributed its first documentary, which featured the struggles of 841-pound, Austin resident Renee Williams, who was thought to be the heaviest woman in the world at the time. The film chronicled her search for help that eventually led her to Dr. Now, the only doctor willing to take on such a high-risk patient. Sadly, like many morbidly obese patients, Williams passed away from a heart attack just two weeks after weight-loss surgery. Her family was so touched by the care and portrayal of Williams' struggles by the Megalomedia crew, they gave the production company permission to release the film with the name World's Heaviest Woman, a title that Williams herself approved prior to her death.

TLC picked up the documentary, and it garnered so much attention, Megalomedia began work on a docu-series called Last Chance to Live, which eventually morphed into season one of My 600-lb Life (via Monagiza).